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br Methods br Results br Discussion Bisphosphonates reduce s
2019-05-04
Methods Results Discussion Bisphosphonates reduce skeletal morbidity in patients with advanced cancers involving bone and have become a recommended component of the multidisciplinary treatment of MBD [1]. However, bone-health benefits have not generally translated into significantly improve
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Much of the focus of expert and public attention has
2019-05-04
Much of the focus of expert and public attention has been on HIV treatment, including test and treat (ie, treatment as prevention) strategies. This is understandable. Treatment for HIV has become extraordinarily effective, costs have dropped substantially during the past two decades, and the potenti
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De acuerdo con el historiador argentino la
2019-05-04
De acuerdo con el historiador argentino, la independencia de las colonias españolas en América es el resultado de una degradación del poder español que había comenzado desde 1795. En primera instancia, el poder de la Corona española se hacía cada vez más lejano, pues la pérdida de la guerra de Españ
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br CONFERENCIA LATINOAMERICANA M XICO
2019-05-04
CONFERENCIA LATINOAMERICANA: MÉXICO, 1961 La carta que Cárdenas le envió en diciembre de 1962 guanabenz Silva Herzog, luego de recibir y leer su libro Hispanoamérica en lucha por su independencia, se destaca por su valoración de los procesos independentistas latinoamericanos y alude a su particip
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Pharmacological inhibition of PI K induces
2019-05-04
Pharmacological inhibition of PI3Kα induces apoptosis of CLL nisoldipine in vitro [5,18], and inhibits CLL migration towards CXCL12 [5]. The PI3Kα/δ inhibitor copanlisib induces significantly greater apoptosis of CLL cells compared to idelalisib (IC50 of 450nM and >10μM, respectively) in vitro and
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But consider the alternative outcomes of so called virtuous
2019-05-04
But consider the alternative outcomes of so-called virtuous plate-clearing. If the additional portion does not displace other consumption—ie, the amount eaten subsequently is not reduced—then total consumption will have increased. A lack of displacement means no reduction in demand for agricultural
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Results from the present study also showed improvement in ti
2019-05-04
Results from the present study also showed improvement in timelines for measles immunisation, which is scheduled at 9 months of age, almost a gap of 6 months from the last vaccine according to EPI schedule for LMICs. Although the major focus up until now has been on reminder messages, the impact of
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Atrial fibrosis is one of
2019-05-04
Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s
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A facility survey from reported that only
2019-04-30
A facility survey from 2003 reported that pitavastatin only 15% of primary health centres provided abortion services. Another study from Rajasthan state revealed that nine districts included 83% of all facilities whereas the remaining 22 districts included only 17%. Within districts too, abortion fa
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Dyslipidemia is characterized by increased total cholesterol
2019-04-30
Dyslipidemia is characterized by increased total cholesterol, LDL-C, and triglyceride levels, and decreased HDL-C levels. However, the association of ApoA1 polymorphism with serum HDL-C level remains controversial. The polymorphisms of ApoA1+84 TC, but not MspI, are associated with serum HDL-C. The
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Any abnormality causing a loss
2019-04-30
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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Conversion of cholesterol to bile acids is the
2019-04-30
Conversion of cholesterol to bile acids is the only significant catabolic pathway for elimination of excessive cholesterol in our body. Bile acids have long been recognized as important physiological agents that facilitate GSK2656157 of dietary fats, steroids, drugs, and lipid soluble vitamins duri
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br We thank Jordi Landier and colleagues for their
2019-04-29
We thank Jordi Landier and colleagues for their comments about our recent Article in . In their work, Landier and coworkers generalise some of our observations on Buruli ulcer in Benin to those for Cameroon, the country that has the fifth highest prevalence of Buruli ulcer worldwide. Briefly, they
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comt inhibitor En este proceso de integraci n
2019-04-29
En este proceso de integración y unidad latinoamericana y caribeña, la imagen política y diplomática de Estados Unidos se vio seriamente mermada por su terrible campaña contra el terrorismo. Su economía se mantiene sumergida en una aguda crisis financiera desde 2008, la más profunda desde 1929. A pe
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El capitalismo ha comprendido m s que cualquier otra
2019-04-29
El capitalismo ha comprendido, más que cualquier otra alternativa crítica, que el sujeto no se orienta recurriendo sólo NS-398 Supplier una racionalidad reflexiva que le ofrece criterios para dar sentido a su acción. El capitalismo, entendido como sistema de dominación, ha alcanzado altos niveles de
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