• Based on these preliminary clinical results with low dose in

  2019-04-26

  

  Based on these preliminary clinical results with low-dose, intermittent zoledronic acid, Hu et al. conducted a randomized phase II clinical study in order to clarify the role of metronomic low-dose zoledronic acid. Sixty breast cancer patients with bone metastases were randomized to receive either 1

• br Discussion CRT has become an established adjunctive treat

  2019-04-26

  

  Discussion CRT has become an established adjunctive treatment to optimal pharmacological therapy in patients with advanced CHF, diminished LV function, and intra-ventricular conduction delay [8]. Despite the benefits of CRT including improvements in exercise capacity, functional class, and ventri

• For all analyses a P

  2019-04-26

  

  For all analyses, a P-value Results A total of 229 patients completed the survey, representing 44% of all ICD patients presenting to the Sunnybrook Health Sciences Center ICD clinic during the study period, of which 78% reported receiving the influenza vaccine. Table 1 summarizes the characteristi

• Case reports br Discussion RV perforation

  2019-04-26

  

  Case reports Discussion RV perforation is a rare but serious complication of PPM and ICD implantation. It is diagnosed when at least the tip of a passive fixation lead or the screw of an active fixation lead passes through the myocardium and extends into the pericardial cavity [1]. This complica

• El ansia renovadora que suscita tambi n se crea y

  2019-04-25

  

  El ansia renovadora que suscita también se crea y re-crea en los paratextos ilustrados, que en cierto modo también sugieren una performatividad discursiva aplicada a la realidad convulsa de México en la revista Futuro, que puede observarse en la imagen y que se ha titulado, “Defensores del orden”.

• br Conflict of interest br Introduction The use of implantab

  2019-04-25

  

  Conflict of interest Introduction The use of implantable defibrillation devices such as an implantable cardioverter–defibrillator (ICD) or a cardiac resynchronization therapy device with a defibrillator (CRT-D) is the primary therapy for improving prognoses of patients with life-threatening ve

• ceramide br Conflict of interest br Ethics br Acknowledgment

  2019-04-25

  

  Conflict of interest Ethics Acknowledgment This study was supported by TRF Grants from the Senior Research Scholar Grant, Thailand Research Fund Grant number RTA5580004, and the Higher Education Research Promotion and National Research University Project of Thailand, Office of the Higher Ed

• Introduction The assessment of hormonal receptor HR and huma

  2019-04-25

  

  Introduction The assessment of hormonal receptor (HR) and human epidermal growth factor receptor-2 (HER2) status by immunohistochemistry (IHC) groups breast cancer into three major subtypes: 1) luminal-like subtype (HR positive/HER2 negative); 2) HER2 subtype (HER2 positive and HR negative/positive

• br Discussion Prehabilitation is a program to

  2019-04-25

  

  Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and

• La incorporaci n de los atributos culturales asociados

  2019-04-25

  

  La incorporación de los atributos culturales asociados EAI045 la población indígena en las instituciones religiosas, entre ellos el idioma, fue de vital importancia en el desarrollo, especialmente dinámico a partir de los años cincuenta del siglo xx en distintas instituciones de inspiración evangéli

• br Discussion There are many reports on the effectiveness of

  2019-04-24

  

  Discussion There are many reports on the effectiveness of pacing therapy for hypertrophic obstructive cardiomyopathy. Fananapazir et al. reported that long-term right ventricular apical pacing improved both the left ventricular outflow tract gradient and subjective symptoms [3]. Maron et al. repo

• In the management of BrS patients it

  2019-04-24

  

  In the management of BrS patients, it is important to avoid or treat certain drugs or circumstances such as a febrile state, electrolyte disturbances (hyperkalemia and hypercalcemia), and the use of class Ia/Ic antiarrhythmic drugs, vagotonic agents, beta-adrenergic antagonists, tricyclic antidepres

• br Materials and methods br Results br Discussion

  2019-04-24

  

  Materials and methods Results Discussion Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common type of primary bone malignancy [20]. Over the past few decades, the introduction of combinatorial chemotherapy has improved the 5-year overall survival rate of

• br Outstanding questions br Conflict of interest

  2019-04-24

  

  Outstanding questions Conflict of interest Acknowledgments This work was supported by the Dutch Cancer SocietyUL2015-7599 KWF (EZ). Platelets and cancer metastasis Blood platelets play a primary role in wound healing and hemostasis. Since the first observation made (on himself) by the s

• Additionally the selection for subcutaneous ICD

  2019-04-24

  

  Additionally, the selection for subcutaneous ICD implant is based on pre-implant electrographic body surface mapping. The sensing algorithm for this system depends on the surface elecrtrocardiogram (ECG) morphology, specifically the R-and T-wave amplitudes, R/T and R/P ratios, QRS duration and QT in

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