• Appendiceal perforation following BTA noted in our two cases

  2018-11-12

  

  Appendiceal perforation following BTA noted in our two cases may have occurred because of appendicolith dislodgement at the moment of injury. An appendicolith (appendiceal calculi, appendiceal enterolith, or appendiceal lithiasis) is a conglomeration of firm, dense feces with some mineral deposits.

• Diffusion weighted MRI has also

  2018-11-12

  

  Diffusion-weighted MRI has also been used to provide an accurate diagnosis of ISCA. Although MRI has many advantages regarding the differential diagnosis of an intramedullary tumor, computed tomography (CT) scans are commonly used in an emergency department to exclude the presence of a hematoma in a

• The clinical application of IR

  2018-11-12

  

  The clinical application of IR thermography was first introduced in 1956, and it was found that the skin temperature over a cancer in a breast was higher than that of normal tissue. With the advancements in IR camera technology featuring higher sensitivity and computer image analysis, it is suitable

• br Materials and methods We revised

  2018-11-12

  

  Materials and methods We revised a set of criteria for TPA to include (1) Glasgow Coma Scale (GCS) score ≤13, (2) systolic blood pressure (BP) ≤90 mmHg, (3) fall of more than 6 m in height, and (4) head, neck, or torso gunshot wound (Table 1). When an injured patient meets the TPA criteria, the t

• parp inhibitors Major nonintubated VATS pulmonary resections

  2018-11-12

  

  Major nonintubated VATS pulmonary resections, such as segmentectomy or lobectomy, usually require a longer surgical time and intensive hilar manipulation. Therefore, appropriate conscious sedation with amnesia is required for our patients to tolerate the uncomfortable decubitus position for hours in

• The diagnosis of VPS induced bowel perforation is often diff

  2018-11-12

  

  The diagnosis of VPS-induced bowel perforation is often difficult and predominantly depends upon the clinical manifestations, abdominal X-ray, ultrasound, and CT results. Typically, bowel perforation is considered in shunted patients with unexplained fever or prominent abdominal symptoms. Additional

• However different types of events such as anti

  2018-11-12

  

  However, different types of events, such as anti-inflammatory, anti-atherosclerotic and anti-immunomodulatory effects, have not yet been well explained and further focused studies are required to explore these properties to establish an optimized conventional drug therapy for cardioprotection [13].

• br Conclusion Two classes of potential natural chemopreventi

  2018-11-12

  

  Conclusion Two classes of potential natural chemopreventive agents as described in this review have been extensively studied and many other compounds are under investigation for their regulation of this protective mechanism. Gaining a better understanding of the molecular mechanisms associated wi

• In mESC cultures cells take on

  2018-11-12

  

  In mESC cultures, trk receptor take on a mesendodermal fate before being committed to either mesoderm or DE (Tada et al., 2005). Activin is used as a surrogate for nodal as they both activate Smad2/3 signaling via activation of the Alk4 receptor (Schier, 2003). In the mesendoderm population, high c

• A current limitation in studying neuronal differentiation

  2018-11-12

  

  A current limitation in studying neuronal differentiation using cultured NSPCs is that the rate of neuronal differentiation of adult NSPCs is rather incomplete: when standard protocols of growth-factor withdrawal are used, only 8%–30% of NSPC progeny differentiate toward the neuronal lineage (as mea

• To the best of our knowledge only

  2018-11-12

  

  To the best of our knowledge, only three metabolites, L-threonine, butyrate, and vitamin C, have been identified so far that act as epigenetic modulators of ESC self-renewal and/or somatic cell reprogramming (Mali et al., 2010; Shyh-Chang et al., 2013; Wang et al., 2009). Interestingly, L-threonine,

• br Methods br Results The distribution of individual Ct

  2018-11-12

  

  Methods Results The distribution of individual Ct values and existing outliers is depicted in Fig. 1. Notably, we observed Ct values in the range of 16 to 29 (Table 2). Reference genes were minimally less expressed in control BMSCs compared to OA-BMSCs. In numbers, these differences in gene ex

• The expansion and maturation of mature ECs and EPCs requires

  2018-11-12

  

  The expansion and maturation of mature ECs and EPCs requires the addition of pro-angiogenic growth factors such as VEGF. With regards the translation of cell-based therapies into clinic, it is of interest to avoid the expensive and controversial use of recombinant growth factors. The supplementation

• Inflammatory changes are observed in

  2018-11-12

  

  Inflammatory changes are observed in AD brains, particularly at the vicinity of senile plaques. They are abundant in activated microglia, which are the resident macrophages in the central nervous system, in both human AD samples (Mattiace et al., 1990; Perlmutter et al., 1990) and transgenic mouse m

• Germ and somatic cells or pluripotent and differentiated cel

  2018-11-12

  

  Germ and somatic cells, or pluripotent and differentiated inhibitor of apoptosis can be distinguished on the basis of their epigenetic states (Boland et al., 2009; Okita et al., 2007; Takahashi and Yamanaka, 2006; Yamanaka, 2012). We previously demonstrated that epigenetic reprogramming following so

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