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The model proved useful for identifying the most
2018-11-06
The model proved useful for identifying the most influential walkability categories for each type of walking. In the case of walking for recreation, all of the walkability categories were significant, but the most influential (with moderate correlations) were greenspace, experience, traffic safety,
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Chemical burns constitute approximately of all burn cases an
2018-11-06
Chemical burns constitute approximately 10.7% of all burn cases and 2.2% of all major burn cases in Taiwan. Furthermore, they have been estimated to cause 30% of all burn-related deaths. The burn depth can often be difficult to assess, as burns that appear superficial might be associated with severe
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AMI5 inhibitor The inhibitory preference of B eurycoma and D
2018-11-06
The inhibitory preference of B. eurycoma and D. microcarpum extracts for α-glucosidase over α-amylase observed in this study is of interest as it may give the extracts pharmacological advantage over acarbose, a widely used synthetic oral hypoglycemic drug. Acarbose inhibits both α-amylase and α-gluc
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br Conclusions br Introduction Genetically modified organism
2018-11-06
Conclusions Introduction Genetically modified organisms (GMOs), also known as genetically engineered or transgenic organisms, for use as human foods or animal feeds are commonplace nowadays. On November 19, 2015, the Food and Drug Administration (FDA) of the United States approved the first-ev
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In this study we have successfully created D SFEBs
2018-11-06
In this study we have successfully created 3-D SFEBs from undifferentiated induced pluripotent stem (iPS) Lomustine that accurately recapitulates aspects of the development of the cortex and cortical networks. In order to facilitate the creation of SFEBs that approximate an in vivo frontal cortex a
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br Materials and methods br Acknowledgments br Introduction
2018-11-06
Materials and methods Acknowledgments Introduction Human embryonic stem 25-hydroxyvitamin d3 (hESCs) offer the potential to regenerate any cell in the human body. Initially, many studies utilized serum-containing media to develop differentiation protocols for target cell types (D\'Amour et
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Epigenetic mechanisms are essential for normal brain develop
2018-11-06
Epigenetic mechanisms are essential for normal purchase apexbio calculator development and function and dysregulation in chromatin regulation results in neurodegenerative disorders, such as Alzheimer disease (Graff and Mansuy, 2009). It has been shown that expression of cell cycle-related proteins
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Thus various experimental approaches have been undertaken to
2018-11-06
Thus, various experimental approaches have been undertaken to determine the exact cellular origin of HSCs in different animal models. Constant cell labeling and time-lapse imaging performed during mouse ESC cultures and BL-CFC development have shown that the hemangioblast generates hematopoietic cel
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Identification of miRNA targets is the most important aspect
2018-11-06
Identification of miRNA targets is the most important aspect in understanding the mechanisms by which miRNAs control cell behavior (Huang et al., 2010; Ivan et al., 2008). Several genes have been identified as miR-210 target genes including Casp8ap2, e2f3, ephrin-A3, neuronal pentraxin 1, MNT, RAD52
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There is evidence from our study of extreme resilience
2018-11-06
There is evidence from our study, of extreme resilience in hepatocytes isolated from patients with metabolic liver disease and for recovery of hepatic function when the hepatocytes are removed from the donor. For example, ammonia metabolism improved in the PHO, CN, and CHF cases in cells cultured fo
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br Introduction Stem progenitor cells
2018-11-06
Introduction Stem/progenitor glycogen synthase kinase (SPCs) capable of multipotent differentiation can be mobilized from bone marrow and adipose tissue, enter the blood stream and migrate to peripheral sites where they may facilitate recovery from injuries (To et al., 1997; Gil-Ortega et al., 20
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blasticidin br Introduction Both the excess obesity and the
2018-11-06
Introduction Both the excess (obesity) and the lack/atrophy (lipodystrophy) of adipose tissue are associated with altered metabolism and lead to major diseases. In particular, the prevalence of obesity-linked diseases has increased worldwide during the past 10years (Savage et al., 2007). The chro
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Among six pluripotency regulators examined only NANOG and
2018-11-06
Among six pluripotency regulators examined, only NANOG and POU5F1 were downregulated by 2days of LY364947 treatment, which impaired DE competence. NANOG is a direct target of Nodal/Activin signaling, and the maintenance of its expression requires active Nodal/Activin signaling (Xu et al., 2008; Cham
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br Materials and methods br Results br Discussion Cell
2018-11-06
Materials and methods Results Discussion Cell-based siRNA microarrays have made it possible to analyze phenotypic changes in cells, including increases or decreases in cellular products and variations in cell morphology. Such methods also provide advantages over conventional methods, such a
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RA NT N neurons have been shown to express a
2018-11-06
RA/NT2N neurons have been shown to express a broad spectrum of neurotransmitter markers in vitro, including glutamatergic (Podrygajlo et al., 2009; Coyle et al., 2011), cholinergic (Guillemain et al., 2000; Saporta et al., 2000), GABAergic (Yoshioka et al., 1997; Guillemain et al., 2000; Saporta et
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