• Introduction Researchers have long followed

  2019-05-29

  

  Introduction Researchers have long followed the strategy that in order to achieve a fuller understanding of the causes of disease and how they can be prevented, it is necessary to study the biochemical and physiological processes involved in the etiology of disease. As I have argued in previous pap

• In silico prediction software SIFT PolyPhen CADD

  2019-05-29

  

  In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com

• GSK503 Heat shock facilitates the folding of various

  2019-05-29

  

  Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is

• Partamos primero de la v ctima sacrificial Fernando Valle

  2019-05-28

  

  Partamos primero de la víctima sacrificial: Fernando Valle. Desde su juventud, Fernando es aislado de la sociedad. Su familia lo rechaza, como explica al médico-narrador (120). Una víctima “sacrificable”, según Girard, tiene que ser alguien diferenciado de la sociedad; las víctimas son seres margina

• Limitations of meta analyses are often based

  2019-05-28

  

  Limitations of meta-analyses are often based on the strength of the data available. Only 26% of the eligible studies were judged to be at low risk of overall bias in this analysis. Other studies may have been at low risk for bias but failed to report information necessary for this determination. All

• Several mechanisms have been proposed Due to

  2019-05-28

  

  Several mechanisms have been proposed. Due to a greater birth interval, children who are breastfed will enjoy a greater period of exclusive parental attention as either the only child or youngest child. This exclusivity might have an effect on intelligence. It has been consistently observed that the

• La entrega del n mero correspondiente al

  2019-05-28

  

  La entrega del número 57, correspondiente al segundo semestre de 2013, ofrece la sección Mirador Latinoamericano, donde se abordan distintos aspectos de la cultura y la literatura en nuestra América. En primer lugar, en el artículo “Crítica literaria y opinión pública: polémicas literarias en Colomb

• Venous gangrene treatment is based on therapeutic anticoagul

  2019-05-28

  

  Venous gangrene treatment is based on therapeutic anticoagulation and thrombolytic therapy. Low-molecular weight heparin is a good choice for patients with active cancer and for pregnant women with good renal function, whereas heparin is used as an alternative in patients with poor renal function.

• br Conflict of interest br

  2019-05-28

  

  Conflict of interest Introduction Gastric cancer is a major cause of cancer deaths worldwide, particularly in East Asia. Metastatic gastric cancer is associated with poor outcomes. The median overall survival of metastatic gastric cancer ranges from 9 to 13 months despite treated with systemic

• Introduction Bone is a very dynamic tissue resulting from co

  2019-05-28

  

  Introduction Bone is a very dynamic tissue resulting from coordinated phases of formation and resorption called bone remodelling. Additional to its role in phosphocalcic homoeostasis, bone remodelling process is necessary for bone growth, for renewal of cellular and extracellular matrix components

• We examined pharmacologic exposures among

  2019-05-28

  

  We examined pharmacologic exposures among the subset of women diagnosed with breast cancer on or after 1995 (N=620) and found that over two thirds (70.8%) received adjuvant endocrine therapy prior to hip or po1 Supplier fracture, including 30.8% who received tamoxifen only, 23.1% who received aroma

• br Conclusion br Conflicts of interest br Clinical

  2019-05-28

  

  Conclusion Conflicts of interest Clinical case The worldwide estimated prevalence of cardiovascular implantable electronic device (CIED) infection is 1–2%. Prompt removal of infected devices ensures survival [1–4]. We report successful extraction of a lead from an infected CIED by using an

• Despite our best efforts the

  2019-05-28

  

  Despite our best efforts, the cause of SCD in young individuals is sometimes not established; no cause is identified in up to 40% of cases. Importantly, whether a cause of death is established or not, the possibility of an underlying inherited cardiac disorder remains in many cases, including the po

• br Therapy for the CPVT br

  2019-05-28

  

  Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele

• Concurrent with the clinical evaluation of the family the ge

  2019-05-28

  

  Concurrent with the clinical evaluation of the family, the genetic findings from a molecular autopsy may help to elucidate the cause of death in the decedent, as well as provide a basis for cascade genetic testing of at-risk family members. Offering cascade genetic testing to asymptomatic relatives

16133 records 1033/1076 page Previous Next First page 上5页 10311032103310341035 下5页 Last page