Our study showed that neurite length and

2018-10-20

Our study showed that neurite length and the ratio of apoptotic compund w in FALS- and FUSH517D/H517D iPSC-derived neurons were the same as in control motor neurons. With several stresses especially in glutamate treatment, however, FALS- and FUSH517D/H517D HB9-positive motor neurons exhibited shorte

Among the epigenetic aberrations of iPSCs

2018-10-20

Among the epigenetic aberrations of iPSCs, DNA methylation is of particular importance. Previous studies showed that unique de novo differentially methylated (DMR) or hydroxymethylated regions (hDMR) are present in iPSCs compared with hESCs (Lister et al., 2011; Wang et al., 2013). Furthermore, the

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2018-07-29