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In patients with surgically corrected CHD the anatomic posit
2019-04-17
In patients with surgically corrected CHD, the anatomic position of the atriotomy scar as the arrhythmogenic substrate is commonly found in the free wall and not in the septum [8]. The cause of this large area of low voltage (“atrial myopathy”) is unclear. Possible explanations include interruption
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br Case report A year old man with
2019-04-17
Case report A 50-year-old man with no known systemic diseases presented to our facility with a growing huge mass at his left flank and numbness of the left leg. Five years earlier, there was only a small lump over his left flank. However, the soft tissue lesion gradually enlarged, accompanied by
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br The past decade has seen increasing global policy
2019-04-17
The past decade has seen increasing global policy attention to nutrition. Concrete steps have been taken to construct a global governance architecture for nutrition and also to mobilise resources for action. Efficacious, low-cost interventions exist, and there is greater consensus around technical
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br Material and methods br Results Thirty one patients
2019-04-16
Material and methods Results Thirty-one patients were enrolled consecutively, in this randomized study, between January 2010 and March 2012. The mean age was 65.5±13.7 years. The proportion of patients with primary prevention indication was 25.8% and ischemic cardiomyopathy was 29.0%. All repo
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br EL CONTEXTO DE LAS
2019-04-16
EL CONTEXTO DE LAS NEGOCIACIONES Y LA AGENDA BILATERAL El avance de Cuba en el fortalecimiento de sus vínculos con América Latina y el Caribe ha sido destacado. En marzo y junio de 2009, Costa Rica y El Salvador, respectivamente, restablecieron relaciones diplomáticas con la Isla, con ello, toda
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The mechanism leading to the gelatinous transformation may i
2019-04-16
The mechanism leading to the gelatinous transformation may involve inhibition of tyrosine kinase activity by tyrosine kinase inhibitors (TKI) leading to blockage of downstream signal pathways, affecting extracellular matrix deposition, adipocyte differentiation and angiogenesis. Moreover, the catabo
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We have received funding from
2019-04-16
We have received funding from the Wellcome Trust to develop a global atlas of podoconiosis. We aim to advance new knowledge on the geographical distribution and spatial epidemiology of the disease. A first step in this work will be to establish the geographical absence of disease by applying an evid
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Severe ECG abnormality associated with systolic dysfunction
2019-04-16
Severe ECG abnormality associated with systolic dysfunction of our DM1 patients. Some degree of electro-mechanical correlation has been demonstrated in several previous studies on DM1 subjects. DM1 patients with prolonged PR or QRS intervals are at four-times higher risk to develop LV systolic dysfu
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Although these studies demonstrated the efficacy of pacemake
2019-04-16
Although these studies demonstrated the efficacy of pacemaker treatment for preventing or reducing VVS, all 3 trials were retrospective and uncontrolled [10]. Therefore, RCTs of cardiac pacing in VVS were proposed in the late 1990s. The era of RCTs: is pacemaker efficacy due to a placebo effect?
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Another cm irregular and lobulated
2019-04-16
Another 11 cm, irregular, and lobulated mass was found in the subareolar region of the left breast. The mass showed interior septation, with solid and fluid components, fluid-hyperdense fluid component level, and enhancement of the solid component after intravenous sr9009 administration (Fig. 3); o
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Pain flare defined as a temporary
2019-04-16
Pain flare, defined as a “temporary worsening of bone pain in the treated metastatic site” [2], has been previously documented as a side effect of radiopharmaceutical and hormonal therapy [2,10,11]. Although it is a recognized side-effect of radiation treatment as well, only recent studies have atte
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All patients with rickettsial infections reported by Dittric
2019-04-16
All patients with rickettsial infections reported by Dittrich and colleagues presented with fever at admission, and few patients presented with typical eschars of inoculation (only 3·6% of patients with murine typhus and 6·7% with scrub typhus). This finding might be a result of poor awareness about
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Although high and variable frequencies of sickle cell trait
2019-04-15
Although high and variable frequencies of sickle cell trait in different ethnic groups in Uganda have been reported previously, those data were from around 70 years ago and were based on small sample sizes. Thus, the findings of Ndeezi and colleagues provide a contemporary overview that is nationall
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Previous studies have demonstrated localization of miR stain
2019-04-15
Previous studies have demonstrated localization of miR-21 staining in stromal e-mail of OSCC associated with the tongue and mouth floor—this might be a useful prognostic predictor. We also observed miR-21 staining in the stromal cells of tumors. However, since multiple lines of evidence indicate th
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The canonical or catenin dependent
2019-04-15
The canonical, or β-catenin dependent, Wnt signaling pathway is critical for the regulation of osteoblast proliferation and survival [95]. Soluble inhibitors of the canonical Wnt pathway such as Dickkopf (DKK1), produced by OBL, and sclerostin, from osteocytes, play important roles in the regulation
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