• br Case report A year

  2018-10-25

  

  Case report A 56-year-old male patient was referred from the rheumatology clinic with symptoms of pain in multiple joints, morning stiffness, muscle weakness, and skin rash for several months. The abduction, adduction, flexion, and extension of the shoulders and the hips of the patient were teste

• Human epidermal melanoblasts and melanocytes can be cultured

  2018-10-25

  

  Human epidermal melanoblasts and melanocytes can be cultured with MDMDF and MDMD with a slight modification. Supplementing MDMDF with transferrin and ET-1 (i.e., MDMDFα) can serially grow and passage human melanoblasts (approximately 90%) and melanocytes (approximately 10%), and MDMD supplemented wi

• br Introducci n Despu s de

  2018-10-25

  

  Introducción Después de más de 20años de estudiar, investigar y enseñar en el campo de los estudios de género, llegó el momento de formular las reflexiones surgidas en el camino en torno al concepto que, dentro de dicho campo, opera como “punto nodal” (point de capiton). Esto quiere decir que el

• Este texto aporta nuevas evidencias a

  2018-10-25

  

  Este texto aporta nuevas evidencias 5-Iodotubercidin un campo de investigación en crecimiento: los estudios sobre los enfrentamientos en torno a las políticas de educación sexual, de los cuales destacan algunos trabajos. En México, se analizan dos momentos históricos en la construcción de la laicida

• Pyridoxal isonicotinoyl hydrazone Los centroamericanos dice

  2018-10-25

  

  Los centroamericanos, dice el MMM, “no se pueden quedar y no tienen Pyridoxal isonicotinoyl hydrazone dónde ir, expulsados por la pobreza y la amenaza inminente de muerte en el país de origen; extorsionados por el crimen organizado, secuestrados y ejecutados en el país de tránsito, y deportados si l

• br Introduction For a healthy and productive life

  2018-10-25

  

  Introduction For a healthy and productive life, good sleep is essential, which has prompted studies on how comfortable sleep can be achieved (Ishiguro et al., 2006). For comfortable sleep, it is very important to create an indoor thermal environment, which could still be improved. Understanding t

• The in vitro production and

  2018-10-24

  

  The in vitro production and expression of ECM proteins collagens I and IV and laminin differed between the perivascular derivatives. In the body, pericytes produce ECM in the subendothelial basement membrane of capillaries, while both vSMCs and pericytes produce ECM in the tunica media layer of larg

• Our studies show that only a subpopulation

  2018-10-24

  

  Our studies show that only a subpopulation of hESCs at the top of the hierarchy possesses an extensive capacity for self-renewal. Polanco et al. recently showed that AM251 in this compartment could reestablish the continuum of cell states seen in unfractionated cultures (Polanco et al., 2013). Usin

• By continuously observing hundreds of individual HSCs

  2018-10-24

  

  By continuously observing hundreds of individual HSCs and their progeny during differentiation, we can exclude a change in cell-cycle length in HSPCs upon GADD45G expression, which was unexpected, because studies on solid tissue you can check here reported a G2/M cell-cycle arrest mediated by GADD4

• In addition to apoptosis we investigated the occurrence of D

  2018-10-24

  

  In addition to apoptosis, we investigated the occurrence of DNA lesions in response to genotoxic insults. Using LORD-Q analyses, a novel sensitive technique to quantify DNA lesions (Lehle et al., 2014), we found that, despite their elevated apoptosis sensitivity, iPSCs accumulated significantly less

• Based on these principles we speculated

  2018-10-24

  

  Based on these principles, we speculated that the use of rBC2LCN as a cargo of cytotoxic agent would provide an efficient strategy to eliminate hPSCs. Here we generated a recombinant lectin-toxin fusion protein by fusing rBC2LCN with 23 kDa of a catalytic domain of Pseudomonas aeruginosa exotoxin A

• citco The activity of CXCL through CXCR

  2018-10-24

  

  The activity of CXCL12(5-67) through CXCR3 receptor has been shown before (Denoyer et al., 2012; Zhu et al., 2009). Here we aimed to confirm this finding using CXCL9, a natural ligand of CXCR3. NSCs pre-treated with CXCL9 were not susceptible to the CXCL12(5-67) apoptotic effects. The effect of CXCL

• Pax is a well known neurogenic transcription factor

  2018-10-24

  

  Pax6 is a well-known neurogenic transcription factor that is essential for the development of multiple neural tissues (Gehring and Ikeo, 1999; Georgala et al., 2011; Zhang et al., 2010). Due to its important role in neuronal development, Pax6 was often included in the initial screening for essential

• br Results br Discussion We have developed an automated segm

  2018-10-24

  

  Results Discussion We have developed an automated segmentation, classification, and localization measurement algorithm (Figure 7A) for analysis of confocal and two-photon microscopy images of HSCs, osteoblasts, and bone obtained through intravital microscopy of mouse bone marrow. In particular

• br Results br Discussion The

  2018-10-24

  

  Results Discussion The Wnt signaling pathway has emerged as the dominant self-renewal pathway for various adult-type stem cells and is required for maintenance of embryonic as well as induced pluripotent stem cells. In the hematopoietic system, only mild increased Wnt dosages result in higher

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