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Instead of introducing extra hardware or hardware
2020-02-04
Instead of introducing extra hardware or hardware modification, software-based CFC techniques just insert extra checking instructions into the source code of the target program at compile time so as to have the target program do checking jobs itself. Preeminent software-based CFC techniques proposed
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br Study design br Results We enrolled
2020-02-04
Study design Results We enrolled 50 subjects awaiting SOT (15 kidney, 14 liver, 1 liver + small bowel, 11 lung, 9 heart) and 50 controls (Table 1) who were similar with respect to median age (subjects 49.1 yrs., controls 48.6 yrs.) gender (64% male subjects and controls), and CMV-seropositivit
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In BBR was reported to increase LDL receptor LDLR
2020-02-04
In 2004, BBR was reported to increase LDL receptor (LDLR) gene expression by stabilizing LDLR mRNA [4]. Following this report, the same groups conducted additional studies predominantly in HepG2 cells, with similar effects being observed [8], [11], [12], [4]. In addition to LDLR-mediated LDL cholest
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br Results br Discussion The ubiquitin system has
2020-02-04
Results Discussion The ubiquitin system has in recent years become an exciting area for drug discovery (Cohen and Tcherpakov, 2010), as multiple enzymatic steps within the ubiquitylation process are druggable. The potential of targeting the ubiquitin-proteasome pathway was first demonstrated i
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Elevation of plasma glucocorticoids as well
2020-02-04
Elevation of plasma glucocorticoids as well as a sympathetic activation are highly adaptive mechanisms allowing the individual to cope in various situations [39]. Novelty-induced increase in locomotor activity, characterizing the bold fish herein, accompanied by elevated glucocorticoids is a well-es
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br Amygdala microcircuitry and fear learning Recent work has
2020-02-04
Amygdala microcircuitry and fear learning Recent work has begun to dissect functional amygdala circuits that are responsible for the acquisition and expression of fear learning. Ciocchi et al. (2010) identified separable populations of baf312 receptor within the CeAL that have opposite responses
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Organ fibrosis is thought to
2020-02-04
Organ fibrosis is thought to be initiated by repeated or chronic epithelial injury. The current belief is that damaged epithelial pp1 induce an aberrant and unresolved wound repair process by activating fibroblasts via various profibrotic cues. Upon injury, epithelial cells activate the profibrotic
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The photocleaving properties of were studied by performing X
2020-02-03
The photocleaving properties of 1 were studied by performing ΦX174 photocleavage assays. Light irradiation of the mixtures of increasing amounts of 1 with supercoiled DNA caused>90% supercoiled form relaxation and approximately 5% of linearization for the higher concentrations of 1 (1:10bp and 1:2bp
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Uracil residues incorporated into DNA exist transiently
2020-02-03
Uracil residues incorporated into DNA exist transiently since they are subject to removal by the multi-step uracil-initiated DNA dihydrofolate reductase inhibitor antibacterial excision repair (BER) process [2], [14]. In E. coli, uracil-DNA BER is initiated by uracil-DNA glycosylase (Ung), which ca
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As temperatures increase rates of
2020-02-03
As temperatures increase, rates of spontaneous deamination also increase such that hyperthermophilic organisms must have efficient mechanisms for dealing with this potential hazard.8., 9. The hyperthermophile Methanococcus jannaschii has both a dCTP deaminase (encoded by the gene at locus MJ0430) an
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Elevated production of cysLTs in asthma and rhinitis
2020-02-03
Elevated production of cysLTs in Dehydroandrographolide synthesis and rhinitis in general and aspirin-sensitive disease in particular10, 11, 26, 27 has been implicated in causing epithelial cell activation and excessive mucus secretion, which characterize these diseases.2, 28 It is of particular in
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Following Duncan as a ritualized site Tyne Cot provides an
2020-02-03
Following Duncan (1995), as a ritualized site Tyne Cot provides an opportunity for individual tourists to conduct their own acts of remembrance (Edensor, 2000, Iles, 2006). The analysis has also shown that individual acts of writing particular words and phrases in the visitor books are socially shar
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br User knowledge representation Various representation
2020-02-03
User knowledge representation Various representation approaches of user interests and preferences are proposed. In this work, we advocate a multidimensional semantic approach based on Bouzghoub et al. meta-model (Bouzeghoub and Kostadinov, 2005), depicted in Fig. 6, to model the user profile. The
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In the frontal cortex the present study found a
2020-02-03
In the frontal cortex, the present study found a relationship between working memory performance and activated Erk2 expression for the E2-only group, where animals that tended to perform better on the WMC measure tended to have higher activated Erk2 expression. This suggests that there is a unique r
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Although the mechanisms underlying the EP mediated increase
2020-02-03
Although the mechanisms underlying the EP4-mediated increase in the frequency of mEPSCs via PGE2 remain unclear, mechanisms similar to those driven by EP2 may be involved because activation of both these receptor subtypes increases the intracellular concentration of cAMP (Nishigaki et al., 1995, Sug
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