• Recently our group elucidated the role of the

  2018-11-02

  

  Recently, our group elucidated the role of the endothelium and secretion of angiocrine factors in the expansion of mouse and human HSCs (Butler et al., 2010a, 2010b; Kobayashi et al., 2010). We developed a model of endothelial BV6 with autonomous Akt-activation (HUVECs-E4ORF1, referred to as E4+ECs

• The advantage of this D culture system is the capacity

  2018-11-02

  

  The advantage of this 3D culture system is the capacity of the induced retinal tissue to recapitulate precisely the in vivo development. At 25 days old, in-vitro-generated photoreceptors start expressing proteins involved in the phototransduction pathway such as GNAT1, and in the generation of activ

• An important step towards further ACC CSC characterization i

  2018-11-02

  

  An important step towards further ACC-CSC characterization is identification of CD markers which, in combination with CD133, may be used for FACS sorting and multiplexed CyTOF analysis of ACC-heterogeneity and their signaling states. Such studies may significantly advance understanding of ACC-CSC ro

• Some of the cultured cardiac MSCs also stained positive for

  2018-11-02

  

  Some of the cultured cardiac MSCs also stained positive for the mesodermal progenitor marker TBX18 (Mommersteeg et al., 2010; Christoffels et al., 2006); future studies need to be performed in order to address whether some of the PDGFR-α+ and TBX18+ promotion potentially share a developmental origi

• ESCs were first discovered in independently by two groups

  2018-11-02

  

  ESCs were first discovered in 1981 independently by two groups (Martin, 1981; Evans and Kaufmann, 1981) and, while they were initially cultivated in medium containing physiological glucose (Glc) concentrations of 5.5 mM, descriptions of their routine cultivation in 25 mM Glc can be traced back to re

• Several studies have linked expression

  2018-11-02

  

  Several studies have linked expression of CD44 and MMP14 to the CSC population. Data suggest common mechanisms regulating co-expression of these two genes; blockade of the ERK pathway suppressed expression of CD44 and MMP14 and inhibited invasiveness of cancer trpv1 antagonist (Tanimura et al., 200

• The computations were carried out for the

  2018-11-02

  

  The computations were carried out for the experimental conditions of Ref. [3], where inline tube bundles with various distances (steps) between them were studied in cross-flow of liquid alkali metals. The operating chamber of the experimental installation was a rectangular box with an inlet diffuser

• In many ways religiosity is easier to quantify than spiritua

  2018-11-02

  

  In many ways, religiosity is easier to quantify than spirituality. Because of the abstraction involved with the concept, survey research often includes indirect indicators of spirituality, such as the item referred to in Table 1. This type of measure demonstrates the broadness of spirituality. In so

• Research in the field of child spiritual health is challenge

  2018-11-02

  

  Research in the field of child spiritual health is challenged by the multidisciplinary nature of the concept and the fact that there are subtle differences in language and definitions applied across disciplines, and approaches to presentation of findings. Child spirituality has been referred to as a

• In the present study brain

  2018-11-01

  

  In the present study, orthopox glutathione activity decreased, while brain superoxide dismutase activity (Table 3) increased with increasing doses of caffeine in both SD and NSD. However, no significant effect of sleep-deprivation or sex influence was seen. Sleep-deprivation studies are based on the

• El v nculo entre el militarismo

  2018-11-01

  

  El vínculo entre el militarismo estadounidense y la organización de los trabajadores en sindicatos, es un aspecto importante—aunque rara vez abordado—de discusión del keynesianismo militar, pues apunta al hecho de que no es posible usar un único criterio, particularmente los cambios en la tasa de de

• Introducci n br Caracter sticas estructurales

  2018-11-01

  

  Introducción Características estructurales del sistema energético nacional El funcionamiento del sistema energético nacional se gestó desde las décadas de 1970 y 1980. En ese marco jurídico e institucional, correspondió al Estado, en exclusividad, el manejo de las actividades centrales de los su

• We sought to further investigate the phenomenon of amoxicill

  2018-11-01

  

  We sought to further investigate the phenomenon of amoxicillin/clavulanate susceptibility using comparative genomics. A phylogenetic analysis indicated that a large proportion of MDR and XDR isolates in our dataset were part of a LAM4 clade, which was responsible for the famed Tugela Ferry XDR outbr

• br MS data interpretation by

  2018-11-01

  

  MS data interpretation by database (DB) searching ProteinLynx Global Server (PLGS) v2.5 (Waters) was used for peak picking and DB searching as described previously [3]. The searching DB contains 20,273 human protein entries extracted from UniProtKB/Swiss-Prot Release 2014_01. The DB searching res

• Official government figures forecast cement

  2018-11-01

  

  Official government figures forecast cement demand of 3.5Mt/year by 2019 [22]. The demand projection at the anticipated peak demand phase (2016–2020) will grow 18% per year. This is linked to an expected boom in construction activity that normally occurs in emerging economies [33]. During the peak d

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