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notch signaling As empirical research revealed that
2018-11-15

As empirical research revealed that budget institutions do affect the budget result of the government and its fiscal policy, it is essential to assess the impact of these institutions on the Brazilian budget performance, a topic, to our knowledge, underexplored in the Brazilian literature. Thereby,
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However Aggarwal states that developing
2018-11-15

However, Aggarwal (2004) states that developing countries are not yet entirely familiarized with the use of AD. He argues that these countries are using it as a way of retaliate the traditional users due to their excessive number of AD cases opened against developing countries. He suggests that an o
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niclosamide br Quantitative dataset at the three main stages
2018-11-15

Quantitative dataset at the three main stages of shell calcification In a second approach, GeLC–MS/MS analyses combined to label free quantitative analysis based on spectral counting quantitative method were used to compare the respective abundance of distinct proteins at the initiation (I), rapi
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br La violencia feminicida uno de los principales motivos de
2018-11-15

La violencia feminicida, uno de los principales motivos del éxodo de las centroamericanas Las motivaciones para el éxodo de estos millones de centroamericanas y centroamericanos son diversas. Para Abelardo Morales (2008), y para Carmen García y María Tarrío (2008), la decisión de migrar obedece s
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br Introduction Acquired hemophilia A AHA is a
2018-11-14

Introduction Acquired hemophilia A (AHA) is a condition in which inhibitor autoantibodies are produced against coagulation factor VIII. It is a rare condition, but the associated morbidity and mortality rates are significant. Furthermore, although autoantibodies for other coagulation factors may
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br Acknowledgment The study has been sponsored by a
2018-11-14

Acknowledgment The study has been sponsored by a Russian Science Fund grant (project no. 15-19-00091). Introduction The issue of the flow and heat transfer in cross-flowed tube bundles is among the most practically important ‘canonical’ cases [1,2] of the problem on liquid metal coolant therm
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br Material and methods br Results br
2018-11-14

Material and methods Results Discussion Currently there are no drugs that prevent insulin resistance resulting from diet-induced obesity while simultaneously being anabolic for bone despite the need for such agents to combat the ongoing epidemic of T2D and its deleterious effect on the skel
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Additionally we believe it would
2018-11-14

Additionally, we believe it would have been valuable to investigate the presence of disturbed conditioned pain modulation (CPM) or inefficient descending pain inhibition in the chronic WAD group compared to controls. Subsequently, the efficacy of CPM could have been correlated with the rCBF of regio
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Remarkably Cornelius et al report for the
2018-11-14

Remarkably, Cornelius et al. report for the first time HBV-neutralizing antibodies in all seven so-far tested human recipients of the BM32 vaccine, i.e., of preS antigen without other HBV antigens. Assay of neutralizing antibodies has been difficult because for long time the only HBV-susceptible cel
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Our results that pinpoint the G q
2018-11-14

Our results that pinpoint the Gαq signaling pathway as classificator for the different sepsis courses of patient groups A and B are also supported by a recent GWAS of common variants with respect to the 28-day mortality (Scherag et al., 2016). Among the identified 14 GWAS loci, three are related to
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Schizophrenia is also characterized by abnormalities in
2018-11-14

Schizophrenia is also characterized by abnormalities in the cortical circuitry underlying gamma oscillations elicited by a variety of stimuli and tasks (Uhlhaas et al., 2010). Especially, individuals with schizophrenia exhibit deficits in the auditory steady state response (ASSR) induced by gamma fr
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Alzheimer s disease is the most common
2018-11-14

Alzheimer\'s disease is the most common progressive neurodegenerative dementia and is characterized by the accumulation of plaques and intra-neuronal fibrillary tangles, where the former consists of beta-amyloid peptides (Aβ) that are highly insoluble and toxic (Querfurth and LaFerla, 2010), and the
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GSK2118436 Duchenne Muscular Dystrophy DMD is
2018-11-14

Duchenne Muscular Dystrophy (DMD) is a severe muscle disease affecting 1:3500 male births. DMD is caused by a mutation in dystrophin gene, coding for a protein required for skeletal and cardiac muscle integrity (Mercuri and Muntoni, 2013; Muntoni, 2003; Muntoni et al., 2003). Indeed, dystrophin is a
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The CIMP Atypical subtype features a gene expression signatu
2018-11-14

The CIMP-Atypical subtype features a gene expression signature characteristic of IFN immune response, overlapping with multiple gene sets related to viral infection, and this signature was reproducibly associated with atypical HNSCC in independent patient population. IFNs are best known as mediators
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The most surprising data for us was the behavior
2018-11-14

The most surprising data for us was the behavior of α-synuclein protein; it accumulated in the dopaminergic neurons of the substantia nigra in response to MPTP treatment, and it failed to accumulate during the treatment with KUSs and esculetin (Fig. 9). Related with this, very recently it has been r
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