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Current evidence indicates that the main reservoirs of
2018-10-22
Current evidence indicates that the main reservoirs of zoonotic Cryptosporidium remain livestock, with the potential transmission of C. parvum (= C. pestis (see Slapeta, 2011)), although other species, and genotypes, have been reported in humans but only occasionally (Slapeta, 2013). Susceptibility
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Keeping this in mind the
2018-10-22
Keeping this in mind, the present study isolated the crude mucilage from Z. mauritiana fruit (ZMM) and evaluated its antioxidant activity and functional properties in association with in vitro anti-diabetic effects. Detailed information about the structural and functional characteristics helps us in
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The oxidation of lipids proteins
2018-10-22
The oxidation of lipids, proteins, nucleic acids and carbohydrates generate a variety of damaging breakdown products which thus can lead to the onset of many degenerative diseases [11–15,62,63,69]. Lipid peroxidation of cell structures containing lipids can lead to the generation of different toxic
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It is to be noted that this
2018-10-22
It is to be noted that this cholecystokinin receptor developed strategy may be with following limitations. More specifically, at one fixed signal increase ratio, there were three possible OTA concentrations without considering the exact sensing system. In order to further confirm this potential unc
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br Results br Discussion Controlling the chromosome
2018-10-22
Results Discussion Controlling the chromosome stability of hESCs and their derivatives remains a fundamental challenge in trials of hESC derivative-based cell therapy. In 2004, Andrew and co-workers reported that chromosomal instability during extensive hESC expansion was due to the Etoposide
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One of the major transduction pathways for
2018-10-22
One of the major transduction pathways for apelin signal depends on the interaction with a Gi-protein coupled to the APJ receptor, independently of Ras protein; although dependent on Protein Kinase C (PKC) (Masri et al., 2005). In addition to the adenyl cyclase inhibition pathway, apelin activates E
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GS1101 To define the transcriptome of the ExE
2018-10-22
To define the transcriptome of the ExE lineage in the present study, we analyzed primitive endoderm and trophectoderm markers using qRT-PCR. Interestingly, we found that markers of the primitive endoderm, such as DDAH2, LAMB1, DAB2, AFP and NR2F1 (COUP-TF1), and markers of the trophectoderm, such as
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Main Text br Acknowledgments br Main Text Florence
2018-10-22
Main Text Acknowledgments Main Text Florence, the cradle of the 14th–17th century European Renaissance (French for re-birth), aptly hosted the International Society for Stem Cell Research (ISSCR) Regional Forum on “Stem Cells in Translation” in September 2013. Over 300 delegates from 36 count
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br Materials and methods br Results br Discussion We
2018-10-22
Materials and methods Results Discussion We report that while MM are randomly distributed within BM, 15-h post-transplant, HSC (LSKSLAM cells) preferentially home to be within two OTX-015 of MM. To investigate whether these two cell types could influence the biology of the other, we refine
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br Methods br Results br
2018-10-22
Methods Results Discussion In mammalians, thyroid hormones regulate the metabolic homeostasis, the protein synthesis, and are also involved in the development, and maintenance of the central nervous system (Patel et al., 2011; Di Liegro, 2008). Deficiency of iodine, a fundamental substrate
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UV induced changes in the cornea are largely mediated
2018-10-20
UV-induced changes in the cornea are largely mediated by the up-regulation of pro-inflammatory cytokines such as interleukin (IL)1 (Corsini et al., 1997), IL6 (Di Girolamo et al., 2002), IL8 (Di Girolamo et al., 2002) and tumour necrosis factor alpha (TNFα) (Kennedy et al., 1997) which correlate to
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br Author contributions br Grant
2018-10-20
Author contributions Grant support The study received the Bardhan Research and Education Trust (BRET) (14345) support. Disclosures Acknowledgements Many thanks to the Bardhan Research and Education Trust (BRET) (14345) , which supports research into digestive diseases, for funding the w
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Most of the observed H
2018-10-20
Most of the observed H3K27me3 and H3K4me3 re-patterning and mRNA expression changes of cardiac genes were associated with the optimal reprogramming condition (MGT, Fig. 3). On the other hand, H3K27me3 deposition at fibroblast genes was observed mostly under the optimal reprogramming condition, while
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Using ESNPs to repair damaged tissue in neurodegenerative di
2018-10-20
Using ESNPs to repair damaged tissue in neurodegenerative diseases is an attractive option, as these aa utp are more readily obtained than fetal material. Recent work on the relationship between neural stem cells and blood vessels (reviewed in (Bjornsson et al., 2015) as well as our own transplant w
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Recently human umbilical cord hUC has been
2018-10-20
Recently, human umbilical cord (hUC) has been investigated as a source of tamoxifen citrate with stem/progenitor cell properties. hUC is a desirable source of stem/progenitor cells as it is routinely discarded after delivery, collection is non-invasive and an abundant number of cells are present in
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